Milwaukee Brewers' outfielder Lorenzo Cain hits an RBI-ground out against the Chicago Cubs during the fourth inning Thursday in Chicago. (Kamil Krzaczynski/AP photo)

CHICAGO (AP) — Ian Happ offered Nico Hoerner some friendly advice after he hit the majors’ first homer of 2022.

“Keep hitting more,” Happ cracked. “Yeah, try not to get cold after that.”

It was that kind of opening day for the Chicago Cubs.

Happ had three hits, including a tiebreaking two-run double in the seventh inning, and the Cubs beat the Milwaukee Brewers 5-4 on Thursday.

Hoerner hit a two-run homer and Kyle Hendricks pitched neatly into the sixth, leading Chicago to the victory on a chilly, overcast afternoon at Wrigley Field. Japanese outfielder Seiya Suzuki reached three times and scored in his first big league game.

On a day stuffed full of firsts and debuts, Milwaukee ace Corbin Burnes and catcher Omar Narvaez became the first battery to use baseball’s new electronic pitch-calling system in a regular-season game. The 2021 NL Cy Young Award winner allowed three runs and four hits in five innings.

“Never really actually found the command of the cutter,” Burnes said. “Kind of one of those things, I found it a little bit in the third, but then I just kind of lost it.”

Andrew McCutchen, Willy Adames and Rowdy Tellez each had two hits for Milwaukee, and Lorenzo Cain drove in two runs. McCutchen served as the designated hitter in his first game with his new team after agreeing to a one-year deal last month.

The Brewers erased a 3-1 deficit with two runs in the seventh, but the Cubs went ahead to stay in the bottom half.

With runners on the corners and two outs, Happ hit a drive off Jake Cousins that caromed off the wall in center. Clint Frazier and Willson Contreras scored on Happ’s second double of the day.

The reigning NL Central champions got one back on Cain’s sacrifice fly in the eighth to close the gap, but David Robertson worked the ninth for his first save since 2018 and No. 138 for his career.

Milwaukee went 1 for 10 with runners in scoring position and left nine runners on base.

“It felt like a game, we didn’t time our hits very well,” manager Craig Counsell said.

Aaron Ashby (0-1) got the loss. He was charged with one run and three hits in 1 2/3 innings.

Making his third consecutive opening-day start, Hendricks permitted one run and three hits in 5 1/3 innings. The right-hander, who had a career-high 4.77 ERA last year, struck out seven and walked three.

Chris Martin (1-0) got two outs for the win in his Cubs debut.

The Brewers jumped in front when McCutchen singled and scored the majors’ first run on Cain’s groundout in the fourth. But the Cubs responded with three in the fifth.

UP NEXT: Brewers right-hander Brandon Woodruff and Cubs left-hander Justin Steele start on Friday afternoon. But there is a wintry mix of precipitation in the forecast.

Woodruff went 9-10 with a career-best 2.56 ERA in 30 starts last year. Steele made his big league debut in 2021, going 4-4 with a 4.26 ERA in 20 appearances, including nine starts.