Cleveland Cavaliers guard James Harden (1) knocks the ball out of the hands of Detroit Pistons forward Tobias Harris (12) while going to the basket during the first half in Game 5 of a second-round NBA playoffs series Wednesday in Detroit. (AP Photo/Duane Burleson)

The Cleveland Cavaliers will look to clinch the Eastern Conference second round over the Detroit Pistons in Game 6 tonight.

James Harden scored a playoff-best 30 points and Donovan Mitchell had 21, helping the Cavaliers come back from a nine-point deficit late in regulation and beat the Pistons 117-113 in overtime on Wednesday night in Detroit.

The Pistons led by 15 points in the first half and 103-94 with two-plus minutes left. The Cavs rallied and pulled into a 103-all tie on Evan Mobley’s free throws with 45.2 seconds left.

“That stretch right there says a lot about our progress — mental performance progress and mental toughness progress,” Cavs coach Kenny Atkinson said.

Just before the buzzer, Cleveland’s Jarrett Allen and Detroit’s Ausar Thompson got tangled up and no call was made.

“He fouled Ausar — clearly,” Pistons coach J.B. Bickerstaff said. “He tripped him when he was going for a loose ball.”

Cleveland went on a 13-0 run and held Detroit scoreless for five minutes from late in fourth quarter to midway through overtime. The Cavs went ahead by seven with 2:39 left in OT on Mitchell’s 3-pointer.

Cade Cunningham, who had 39 points and nine assists, made a jumper to pull the Pistons within two points with 25 seconds left.

Harden made one free throw on the ensuing possession and rebounded his missed second attempt. He made another free throw to help seal the win.

The fourth-seeded Cavs will get the first of two chances tonight to advance to face the New York Knicks in the East finals.

If the top-seeded Pistons win, they will host Game 7 on Sunday.

Tip-off today is at 7 p.m. Eastern time.