San Francisco 49ers quarterback Brock Purdy (13) reacts to a touchdown pass to 49ers running back Christian McCaffrey during the second half against the Philadelphia Eagles on Sunday in Philadelphia. (AP Photo/Chris Szagola)

PHILADELPHIA (AP) — Brock Purdy threw a go-ahead 6-yard touchdown pass to Christian McCaffery late in the fourth quarter, San Francisco used a trick play on a TD toss from wide receiver Jauan Jennings, and the 49ers eliminated the defending Super Bowl champion Philadelphia Eagles with a 23-19 wild-card victory Sunday.

The 49ers head to top-seeded Seattle next weekend for an NFC divisional playoff game. The NFC West rivals split the season series.

Purdy threw for 262 yards and got the road win in Philadelphia he failed to get three seasons ago when he was injured in a dismal outing in Philadelphia in a loss in the NFC title game.

Purdy had two passes intercepted in this one by All-Pro cornerback Quinyon Mitchell, but the Eagles scored just three points off the turnovers.

The 49ers could head to Seattle without star tight end George Kittle, who was carted off the field with a right Achilles tendon injury late in the first half.

The Eagles — who won a Super Bowl on a trick play — were foiled by one when Jennings was pitched the ball and rolled right and hit McCaffery on a 29-yard touchdown. The score on the first play of the fourth quarter gave the 49ers a 17-16 lead.

The Eagles would only get Jake Elliott’s 33-yard field goal in the quarter for a brief 19-17 lead.

Philadelphia was again doomed by a lethargic offensive effort that cost it a shot at a repeat championship. Super Bowl MVP Jalen Hurts threw for only 168 yards and a touchdown and the Eagles failed to build off a 13-10 halftime lead by totaling only 36 total yards in the third quarter on 16 plays.

Hurts was incomplete on a last-gasp fourth-and-11 attempt with 43 seconds left that ended their final drive.

No. 2 seed Chicago (12-6) will host the No. 5 seed Los Angeles Rams (13-5).

Matthew Stafford threw a 19-yard touchdown pass to Colby Parkinson in the final minute as Los Angeles rallied to beat the Carolina Panthers 34-31 in a game that was much closer than expected.

The Rams were double-digit favorites on BetMGM Sportsbook against the Panthers (8-10). The Rams jumped to a 14-0 lead, but couldn’t take advantage of first-half turnovers and allowed Carolina to get within 17-14 at halftime.

Stafford, who earned All-Pro honors for the first time in his 17-year career on Saturday, threw for 304 yards, three TDs and had one pick. Puka Nacua, who was a unanimous All-Pro selection, had 10 catches for 111 yards and one TD and also had a 5-yard TD run.

The Rams are back in the divisional round for the second straight season. Last year, they were 13 yards away from eliminating Philadelphia before a sack and an incomplete pass ended their season with a 28-22 loss.

The Denver Broncos (14-3) are the AFC’s No. 1 seed and the Seahawks (14-3) got the top seed in the NFC. Each team earned a bye and will host the lowest remaining seed next weekend.

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