The Detroit Lions are kicking off the season against the Los Angeles Rams on Sunday night, a rematch of an NFC wild-card game. Detroit beat Los Angeles 24-23 on Jan. 14 at home for its first postseason victory in 32 years.

The Lions are 5-2 against Rams when opening the season against each other.

Los Angeles Rams (10-8) at Detroit (14-6) Sunday, 8:20 p.m., NBC/Peacock/Universo

BetMGM NFL odds: Lions by 3 1/2.

Series record: Rams lead 45-42-1.

Last meeting: Lions beat Rams 24-23 on Jan. 14 in Detroit in an NFC wild-card game.

Rams offense: overall (7), rush (11), pass (10), scoring (8).

Rams defense: overall (20), rush (12), pass (20), scoring (19).

Lions offense: overall (3), rush (5), pass (2), scoring (5).

Lions defense: overall (19), rush (2), pass (27), scoring (23).

Turnover differential: Rams minus-2 (T-25); Lions minus-2 (T-25).

Rams player to watch

WR Puka Nacua capped off his outstanding first season by catching nine passes for an NFL rookie postseason record 181 yards and a TD in the playoff loss to the Lions. Nacua missed time in training camp because of a knee injury, but is ready to go to start off his second NFL season.

Lions player to watch

WR Jameson Williams. The third-year player has the potential to become one of the league’s breakout players. Detroit has patiently waited for production from the former Alabama star, drafted No. 12 overall in 2022. He will have plenty of opportunities as the No. 2 receiver behind All-Pro Amon-Ra St. Brown.

Key matchup

Rams OT Joe Noteboom vs. Lions DE Aidan Hutchinson. Noteboom will start at left tackle with starter Alaric Jackson serving a two-game suspension for violating the NFL’s personal conduct policy. Noteboom has been more effective in his career as a swing tackle and spot starter, and the Rams will need him at his best against the disruptive Hutchinson. He sacked Matthew Stafford twice in the playoff win.

Key injuries

Rams RT Rob Havenstein (ankle) is questionable to start after being limited all week in practice. Warren McClendon will take over if the longest-tenured Rams player can’t go. Havenstein was injured in early August. CB Tre’Davious White will make his Los Angeles debut after tearing his Achilles tendon in Week 4 with the Buffalo Bills last season, but fellow CB newcomer Darious Williams is on injured reserve with a hamstring injury. Williams is likely to be replaced in the starting lineup by Cobie Durant, who participated fully in practice Friday despite a hamstring injury. TE Tyler Higbee begins the season on injured reserve after hurting his knee in Detroit last January. … Lions DT D.J. Reader, a key offseason addition, is questionable after being limited all week in practice by the leg injury that ended his season last year with Cincinnati. S Ifeatu Melifonwu is doubtful for Sunday with an ankle injury.