ALLEN PARK, Mich. (AP) — The Detroit Lions put standout center Frank Ragnow on injured reserve, another setback for a banged-up winless team.

The Lions made the move along with signing linebacker Jessie Lemonier off the practice squad and activating kicker Austin Seibert from the COVID-19 reserve list.

Detroit was without tight end T.J. Hockenson and offensive tackle Penei Sewell on Wednesday. Hockenson missed the afternoon session because of a knee injury.

Sewell, the No. 7 overall pick in the draft, had an ankle injury during the Lions’ loss at Chicago on Sunday.

The Lions (0-4) are expected to give center Evan Brown his first career start in his three-year, four-team NFL career on Sunday at Minnesota (1-3). Detroit signed center Ryan McCollum from Houston’s practice squad Tuesday.

Linebacker Romeo Okwara had a season-ending Achilles tendon injury against the Bears.