PHILADELPHIA (AP) — North Carolina crushed all hope of a March Madness miracle in the early going Sunday, getting 20 points and 22 rebounds from Armando Bacot in a wire-to-wire 69-49 runaway over 15th-seeded Saint Peter’s.

The eighth-seeded Tar Heels (28-9) made their record 21st Final Four, and next on their list is none other than archrival Duke and its soon-to-be-retiring coach, Mike Krzyzewski.

Next Saturday in New Orleans will mark the first Final Four meeting — first NCAA Tournament meeting, in fact — between the Tobacco Road archrivals whose campuses are separated by 11 miles.

Two nights earlier, Saint Peter’s (21-12) beat Purdue to become the first 15 seed to advance to an Elite Eight. But the underdog Peacocks are hardly the first team to see grand plans undone by one of the country’s top-line power programs.

After Carolina’s Leaky Black missed a free throw 2 1/2 minutes in, Bacot edged in for the offensive rebound and an easy putback. It gave Carolina a 7-0 lead. In its three tournament wins over Kentucky, Murray State and Purdue, Saint Peter’s had never trailed by more than six.

Late in the first half, Daryl Banks III’s attempted jam was rejected by the front of the rim. It made the Peacocks 5 for 27 on the night, and when Bacot dunked on the next possession, North Carolina led 36-15.

Fousseyni Drame led Saint Peter’s with 12 points and KC Ndefo had 10.

MIDWEST REGION: Kansas 76, Miami 50

CHICAGO (AP) — Ochai Agbaji, David McCormack and Christian Braun powered a dazzling second half for Kansas, and the top-seeded Jayhawks pounded Miami 76-50 on Sunday to advance to the program’s 16th Final Four.

Agbaji scored 18 points, McCormack had 15 and Braun finished with 12, helping Kansas rally after a lackluster start. The Jayhawks trailed by six points at halftime but outscored Miami 47-15 in the final 20 minutes.

Kansas (32-6), the only No. 1 seed left in the NCAA Tournament, won the Midwest for the 13th time with its ninth consecutive victory overall. Next up is the national semifinals and a matchup with Villanova on Saturday in New Orleans.

Kameron McGusty scored 18 points and Isaiah Wong had 15 for No. 10 seed Miami in the program’s first appearance in the Elite Eight. The Hurricanes (26-11) were bidding to get coach Jim Larranaga back to the Final Four for the first time since he led 11th-seeded George Mason there in 2006.

WEST REGION: Duke 78, Arkansas 69

SAN FRANCISCO (AP) — Coach Mike Krzyzewski’s farewell tour is headed to his record-setting 13th Final Four after Duke overwhelmed Arkansas 78-69 on Saturday night in the Blue Devils’ most complete performance of this NCAA Tournament run.

A.J. Griffin scored 18 points, Paolo Banchero added 16 and and second-seeded Duke (32-6) frustrated fourth-seeded Arkansas (28-9) on the offensive end to get back to the Final Four for the first time since Krzyzewski won his fifth championship in 2015.

The Blue Devils were in control for most of the second half, using an 10-0 run after Arkansas had cut the deficit to five points early in the half to open up a big cushion.

Jaylin Williams led Arkansas with 19 points and 10 rebounds and JD Notae had 14 points before fouling out. The Razorbacks shot 41.9% for the game.

SOUTH REGION: Villanova 50, Houston 44

SAN ANTONIO (AP) — Jermaine Samuels had 16 points and 10 rebounds as Villanova advanced to its third Final Four in the last six NCAA Tournaments with a grind-it-out victory Saturday over Houston.

Caleb Daniels added 14 points for the Wildcats (30-7), and fifth-year senior Collin Gillespie’s only made field goal was a clutch shot late.

Villanova shot 28.8% from the field (15 of 52). The Cougars were only slightly better at 29.8% (17 of 57), missing their last five shots and 10 of 11 overall, and they made only one of their of 20 attempted 3-pointers in their lowest-scoring NCAA tourney game ever.

Taze Moore had 15 points and 10 rebounds for the Cougars (32-6), who were denied making consecutive Final Four appearances for the first time since 1982-84.